Treatment For Mycobacterium Tuberculosis

Mycobacterium Tuberculosis

Mycobacterium tuberculosis is oxygen expending bacilli,non-motile,non-capsulated, and mycobacterium tuberculosis non-sporing. Mycobacterium is airborne illness airborne methods transmitted through the air.

Introduction Of Mycobacterium Tuberculosis:-

Mycobacterium Tuberculosis was first discovered by Robert Koch on 24 march 1882 in German. who got the Nobel prize in 1905.

Morphology Of Mycobacterium Tuberculosis:-

Mycobacterium Tuberculosis is thin, straight, marginally bent with adjusted finishes. Ziehl-Neelsen recoloring is helpful for the investigation of the morphology of tubercle bacilli. Zn stains color the tubercle bacilli in brilliant red shading and tissue and different living beings in blue color

Culture Of Mycobacterium Tuberculosis:-

Mycobacterium Tuberculosis develops gradually state shows up around 2 two months. The ideal temperature for development is around 37 degrees celsius and Ph for development is 6.4-7.0.

Different kinds of media utilized for disengagement of tuberculosis bacilli, for example, Petragnani, Dorset egg medium, Middle rivulet, and Dubos medium. Mycobacterium tuberculosis most normally develops in Lowenstein Jensen(LJ) medium. LJ medium comprises of egg, malachite green, glycerol.

  • Egg act as a solidifying agent. 
  • Malachite green provides colors. 
  • Glycerol provides growth.

Laboratory Diagnosis Of Mycobacterium Tuberculosis:-

1. Specimen Collection:- Example assortment relies upon the site of disease contribution.

  • Sputum              – Pulmonary tuberculosis
  • CSF                    – Meningitis tuberculosis
  • Urine                  – Renal tuberculosis
  • Aspirated Fluid  – Bone and joints tuberculosis
  • Biopsy                – Tissue tuberculosis

2. Direct Microscopy Of Mycobacterium Tuberculosis:-

Made smear from the example and recolored by the ziehl-Neelsen method. Evaluating the smear as indicated by the number of bacilli seen.

3. Culture Of Mycobacterium Tuberculosis:-

Culture is a touchy technique for the discovery of mycobacterium tuberculosis. Make concentrated material and vaccinated in two jugs of Lowenstein Jensen medium. Make concentrated material by the Petroff strategy. Spot one jug of Lowenstein Jensen medium within the sight of light and second jug place n dim.

4. Sub-atomic Method For Detection Of Mycobacterium Tuberculosis:- 

These sub-atomic techniques are utilized for the discovery of tubercle bacilli.

  • Polymerase chain reaction(PCR)
  • Ligase chain reaction(LCR)
  • Transcription mediated amplification(TMA)

5. Colony Of Mycobacterium Tuberculosis:-

The colony of mycobacterium tuberculosis is dry, rough, raised, and wrinkled.

6. Treatment Of Mycobacterium Tuberculosis:-

A combination of drugs is used for therapy of mycobacterium tuberculosis most powerful drugs are isoniazid, rifampicin, amikacin, kanamycin, and capreomycin.

7. Symptoms of Mycobacterium Tuberculosis

  • Coughing that at least two or more weeks
  • Coughing with blood.
  • Chest pain and pain with breathing and coughing
  • Unintentional weight loss
  • Loss of appetite, fever, and chills

8. Precautions of TB Patient:-

  • Take all your medicine from time to time until your doctor you off them.
  • Always your mouth is covered when you cough and sneeze.
  • Wash your hand after coughing and sneezing.
  • Don’t use public transportation.
  • Don’t visit public places

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